Generating patterned arrays of photoreceptors
Current Opinion in Genetics and Development, cilt.17, sa.4, ss.314-319, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 17 Sayı: 4
- Basım Tarihi: 2007
- Doi Numarası: 10.1016/j.gde.2007.05.003
- Dergi Adı: Current Opinion in Genetics and Development
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.314-319
- Boğaziçi Üniversitesi Adresli: Evet
Özet
One of the most fascinating topics in biology is to understand the development of highly differentiated cells such as photoreceptors (PRs). This process involves successive steps, starting with the generation of the eye primordium, recruitment and specification of PRs and finally, expression of the proper rhodopsin, the photopigment that initiates the signaling cascade underlying light input excitation. In this review, we describe the sequential steps that take place in the Drosophila eye, from the initial neuronal specification of PRs through their full maturation, focusing specifically on the transcription factors and signaling pathways involved in controlling the precise expression of different rhodopsins in specialized PRs. © 2007 Elsevier Ltd. All rights reserved.