Prediction of binding sites in receptor-ligand complexes with the Gaussian network model
Physical Review Letters, cilt.100, sa.22, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 100 Sayı: 22
- Basım Tarihi: 2008
- Doi Numarası: 10.1103/physrevlett.100.228102
- Dergi Adı: Physical Review Letters
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Boğaziçi Üniversitesi Adresli: Evet
Özet
Residues at the binding sites of the ligand and receptor of several enzyme-inhibitor and antibody-antigen complexes are predicted from the slowest (for the ligand) and fastest (for the receptor) modes of motion by the Gaussian Network Model applied to unbound molecules. © 2008 The American Physical Society.